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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00ee7d847a4fcfb5ed314b04f90de124b106a9504bdcb2e29188833bec4e8a1' 
  AND token = 'FRxBhfm3F/C6QFc5fbsOcBo0Ooo+f6+w/+EH9wUAee0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}