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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e64ebff9b54837139af181555a4f48976193e987e7074cf1c67e81b5b6d854d' 
  AND token = 'hm+aHvU+GX+7DDAYIeVqFd/Rli8DXKI9EmX7lcxlsMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}