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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7a4a1e934653aa7635959a18eb9f2e64e73b740b0bf9685d72ccec8d80e14b' 
  AND token = '+0sM5i6/YqJekn7klo+Muz2K0zdnDujWoT1j5N/+Qr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}