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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e4107e9446b52d2ecf0331691b2b6b96a00a64a8a89a4f314596afce795ffe' 
  AND token = 'S5qOVF/3q/+5A+LDugqbUqoZMnHNtsahAUrqfRYdgpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}