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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e412d3eed8966aef0b21a29f201ed0577cb885f055559f873f3de4f6461f9b' 
  AND token = 'kG6zWa9YI0RH4y5IhSKqDyhPBi7CTCWtOQSeeuV4sfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}