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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80287120d4e84892626363b0a0a43ab10566abf8dba1ffb54ebec95d37a9c98' 
  AND token = 'CVWCwUieCRvsJnR7TbywO2XQ9YWyaupkY6opyZRwVoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}