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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad6e83a226a74cc6cfd8768fecc08bba47f2f2f941929f3ad8bbaa89859fc6f' 
  AND token = 'qZ6A/DyUjtBpjFpbG4pwsnSbcRsuF4VZ3iCnleorMRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}