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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c11234cc80e3dcd62b8bcbc56cad9f9a32197dc48a34841f4a875a1378886b2' 
  AND token = 'XyPn9jd153XzXaIubi6thWne0R3BJfxnbRVPV7CWMqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}