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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c672bbf3f2453e34345cb68d4245c4c64a0ef9f5eec56510b951c97465f6a4' 
  AND token = 'PXO/nWZ+RVb7+2z4exz300rNZQeeiucfsRr8DvK1WuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}