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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2edf4b65036d08321810d37464e347c8a40f4a01d1e81c26fa0cc381be4746de' 
  AND token = '+7e9Y15TfoKLEbVgYUpCKALvCVYLJdiJrgoAkvQI6iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}