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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a579121cde7befd362e02945b3195ac6fa87c33acf85e7a2398f99c53e94aee' 
  AND token = 'b8LN/sdS4SlBKNZ9D0AdYf/tnS/DKlWJLRBFmq0O+MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}