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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0960917e73833b603cf8cf930ac0a6d5b37cf401af987b6a4592b3f3b6c913' 
  AND token = 'Ntw6aIHXEdy1VQnQaJwaVdC7nDAHIvg+yad55ZvJBsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}