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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b6bf3466fd4067f715b5496a762a345b28e0e9c1e9eefc504b6a6e47a8b0ac' 
  AND token = 'xwSACMYyuw41ah0kNa/8iUwRO+09AYDMajyDuP9XL2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}