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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a79b1023ab4391942b2eeb91c38298e00e23a7e738dc09899e0617eb8a20a3c4' 
  AND token = 'I3xKqmR9kKbR6M8mIJ3uxhvOg8jsEYgsgtwWn3MolfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}