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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277ab15a89bac9ea04c049d0c22937dc23d11ee87d98577f19a4607dfac65201' 
  AND token = 'L/Iq2F8t9whbySNC/fCeSglhiBcIp801vT42rCQkSfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}