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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc6afbb6530c01e05627c7c8f0b889920106a53f014d7d08ff281e26f28c0d6' 
  AND token = 'sZy0snnETTO1PjU/gIiV2uwN2bslWaEl85EqC/g8nak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}