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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be441aa2ee368ecd2added990737b2ccab703eae9098accf813662b8c608cb1e' 
  AND token = 'ioVlBbBwtf28Qcnk4kOVYnzlu52FKj+K6YaAD5dF1a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}