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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e608bd15d7af1618c4eb2ef13cdfe6672751ca44e892476ff05b2fa2db8b5f' 
  AND token = 'Tub786qXl1WUN3YnpT9pG0n/rd8yniTO9WdgSohYdtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}