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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ee456b50bd55c5a298a81c733f7b0ecab458c72bb4d0e785b7580899f4cc44' 
  AND token = 'zsQ4Wlh57Qxq7nU31I9nqLChZPbQG6E2GfaHGgZd+9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}