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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4761dbfdec1520267e668a94c24b2e370a1154c4586922d3202b029f240c3d58' 
  AND token = 'UpJhsyBHymrXAokqhT2zCR8oNUgl3e4ISp603FnaZNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}