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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357507e1e133eb4e779ba8343aeb08f0716f14780aa697f3a08d14f297ce1497' 
  AND token = 'HTWK1FLp333gPQ6JM1Qr1WVb0A7/fIMTRQXkE510ELQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}