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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a00258a9ef8250f49406acafd51e0d48047491e3c474941a3862b443627b43' 
  AND token = 'PIiJEe6W4w0QyaEfsXsf0op2j/mMxOZ+oty0n0EWyzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}