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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d68cf6014df1a6fd89bb8ee5cd46ca25dc5e77927ba49c926092d7bedd0cde9' 
  AND token = '+criMHWINKpt4NNSp1G2Z59fNaS5mTqmSrIt0ExN2qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}