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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381b8db8d5eceeb8f4a0d1bb21c0f839eb24929d5a4013406e2c41aae6ec4194' 
  AND token = 'V7LA9lCCt55keXejBp2uaRxHTx7kYODRoTW26oZDZSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}