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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b09c6a0e9f0dc050c09695c72a90f256c81bfcea549717a4d66886ee9f157592' 
  AND token = 'oP7tI9AIdfnsJWavqIb4Py+IC3GXutYxRj8aDmuJsMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}