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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4220d089fdca73c92a46f919bf6178efde8c15747c5ca529df5b447a4ce36f08' 
  AND token = '+0cKogoB+WScd1UDfJKEgWaG3Zztl44yIdiqMfZaawg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}