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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852e5380994da795c553aff065e2c528f6fbdde7ea2d2997b73ba43a131eb4c9' 
  AND token = 'SBbEpv9KM8y8LLj7yyhz1lvzHlR5jfnXWk8m9P3g0xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}