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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1265a5485751b492210de5182ad1aaaa16b5052e170af4f755704e0d4bf6327' 
  AND token = 'dxRuu2/uUO384P0WqkKG7tIwwQiBZ17G9Df/esVm13w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}