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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b2be617865e2953c0eb043f1d2b431c684d7a8620f5ebf328216b9a05fecf5' 
  AND token = 'i542/IMDrBjXcn0VWAFm8CGMAGEX7mH4vT/EBwP8Eho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}