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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6da718718b976457e2592ad9fcfee68cdbeb808509bde67b344ada952d6b07' 
  AND token = 'b6uBlqwzgHcM4+UzRuKHBc5yYlFEvTquvc8MuFNnCic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}