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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d75a0ee185b479f558e0c14903d3966757a0ba090a50e5b676c194d517b8c16' 
  AND token = 'LV/nfVDPGeQxBLSYuYkxbOPQPY0yXOD6OLd84QhUZ5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}