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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f26811aa4da5482c5d784a11acc853bdfff115231429be040dcd225e59e670' 
  AND token = 'G2MyxZSPwdeWTA4+HgfTGjV5sNUOOwNPexM4IXUPw9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}