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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4952eb05257b5051beec9d1244643845b340cdb0b1e9b3d6ef6c9fc6ef6ac249' 
  AND token = 'Nl4soweZrhzRVjR7V2oYALcjxmdtwzyFAg+xHChOk/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}