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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616b7bb90cd27517d6210f5cfc082ed2b83d32af3dc9e8912531ee1077477c45' 
  AND token = 'TiQ+Mvc4tWYSq4qU9nZqeQWJeGfcyt0ruI+kBP9aHkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}