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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5eaf19900a6588be051dd75960b1cf42c39ec4f63d2ca6aad4b10511238e49a' 
  AND token = 'W/k1CEEZ28R1RxEFJCTM4qADsBmlJJEUgqbkXjEC+ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}