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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aebccf7b9c237b78fea7432d37c670cd4b0c410c7e039ec98ed0cb5b68af7cd8' 
  AND token = 'FPm0hENPlp4/kGN++gEqvqfIwKPFTfP2ZnbtdpGbU8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}