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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428034debea33881fbb4c317feef2cdaf1807a6184abc6a21be8e5876df6dea2' 
  AND token = 'fDMakq83FIMJ/h4HITCNFB3j4k/PZJuxv0oo7nFKpmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}