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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c91eb7c0f3eb3ec9640a46edd89141869a634846b6d0d594ad3125ed14edff8' 
  AND token = 'aRiL4hXItiCbtSdJXYRc48Fx9b4aOfTKCbvZropHVI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}