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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c86322044525ed1278331435cd9ca8685e43823717406a633b9d9299212d9c4' 
  AND token = 'RitT4kq6VRlqk+Dcx5gWjM55oHNsuqDlyOBHYr2+s1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}