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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151c9a00cc8478f16f41d9c9c29fcd807259631562f4e042d716e8c0edc74f34' 
  AND token = 'aUMJUo/jFKzAXHjSZ7X1SpyYh7qdrLeYgX01tmbPb9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}