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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916663a7393eed9e6e42bca83acc1186fc7d11e7a8650716b9fec4c40a49148e' 
  AND token = '/sONFOLKQtNI/FT70zbTBdmf+s1rGUnmmLB5sOIWbjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}