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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27216bfa72d3f52aaf92d43e7040230634b416791626bb5d4001dcc85b08b8a' 
  AND token = 'W1rU0adBcn5cQhF0ufwdkYym9aPZHpMOTCk7BjXVvuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}