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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64382624faa8d60c27c6780b39455b2d0455aaa178f8cb759e06984f4224ec9b' 
  AND token = 'oSouiKQlghH9xyo2dL7E+Lq0QrLekI/8XnBi8YSQSmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}