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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fc67b8f26a5d1147f4c765eb8f2d830bcba7fa0e74a3b4593e63db4e79f335' 
  AND token = 'eNMBXSNSSqgxUHv8mK7CmNozKHVPpT5JFEP0WPdL7y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}