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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4428d868736de90a7ff7bfba973c94b725d3f3044d65aca5aef94a1d307955' 
  AND token = 'a2SbdvhFBX6W0W5FOT1DXrHSwL7XssRXbrRk447NpMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}