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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0739b929923196dd5c49a143d9e2b32fd1bd9172576e72217063c4490ecf1c12' 
  AND token = 'bqyjW48zvzbbvtsJ6MlZxgvxXoJM37AMwx5sKosvCWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}