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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9711b3946ccd3b2848fc81d8161be9c60567c4bdfd028e1953b7b16a3537f00' 
  AND token = 'uSAFWyx6hyWS0mGsOAKt/9cMOaYIkENUx0Bq6ORiGwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}