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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec196fa3e202cf8065648bddbc50295d1d28a990f2a6776e6b46b9b660e46498' 
  AND token = 'UVD3yJ1HuUN5TiYADZMXyt09Gmwk862R7bqdr2SjvPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}