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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0189b2b0e1d39c4665f0770fa36dc41364eb59c283ea6be53b309a79615b1ff3' 
  AND token = '9q/OUUECD4PRGlbV74Xifv1uITLL4F0cZ3YrIpfH8Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}