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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cc6640d0ec802af65bf9c3f6d31e5781a7a0d240dde0d4bdf4f8ff4701d441' 
  AND token = '230v5mhBJtAVCx8E3UPtvmLxVHSJkd03hc2dOxs2YVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}